|
|
S-adenosyl-L-methionine + (S)-tetrahydrocolumbamine <=> H+ + S-adenosyl-L-homocysteine + (-)-tetrahydropalmatine
|
2.1.1.117
(S)-scoulerine 9-O-methyltransferase
2.1.1.89
tetrahydrocolumbamine 2-O-methyltransferase
|
–
–
|
|
BRENDA:
BR43929;
BS456368
KEGG:
R04077
MetaCyc:
2.1.1.89-RXN
SABIO-RK:
3808
|
|
|
|
O2 + (S)-reticuline <=> H+ + H2O2 + (S)-scoulerine
|
1.21.3.3
reticuline oxidase
|
–
|
|
BRENDA:
BR36965
KEGG:
R03831
MetaCyc:
RETICULINE-OXIDASE-RXN
|
|
|
|
S-adenosyl-L-methionine + (S)-scoulerine <=> H+ + S-adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine
|
2.1.1.117
(S)-scoulerine 9-O-methyltransferase
|
–
|
|
BRENDA:
BR1438
KEGG:
R03835
MetaCyc:
2.1.1.117-RXN
SABIO-RK:
3591
|
|
|
|
(S)-tetrahydrocolumbamine + O2 + H+ <=> Columbamine + H2O2
|
1.3.3.8
tetrahydroberberine oxidase
|
–
|
|
KEGG:
R03722
MetaCyc:
RXN-8698
|
|
|
|
S-adenosyl-L-methionine + Columbamine <=> H+ + S-adenosyl-L-homocysteine + palmatine
|
2.1.1.118
columbamine O-methyltransferase
|
–
|
|
BRENDA:
BR40576
KEGG:
R03721
MetaCyc:
2.1.1.118-RXN
SABIO-RK:
3482
|
|
|
|
H+ + (-)-tetrahydropalmatine + O2 <=> palmatine + H2O2
|
1.21.3.3
reticuline oxidase
1.3.3.8
tetrahydroberberine oxidase
|
–
–
|
|
BRENDA:
BS442681
KEGG:
R08795
MetaCyc:
RXN-8699
|
|