|
|
paromamine + O2 <=> 6''-dehydroparomamine + H2O2
|
1.1.3.43
paromamine 6'-oxidase
|
–
|
| |
BRENDA:
BR50143
KEGG:
R08896
MetaCyc:
RXN-13165
|
|
|
|
2-deoxy-scyllo-inosamine + NADP+ <=> 3-amino-2,3-dideoxy-scyllo-inosose + NADPH + H+
|
1.1.1.329
2-deoxy-scyllo-inosamine dehydrogenase
|
–
|
| |
BRENDA:
BR50138
KEGG:
R10130
MetaCyc:
RXN-13118
|
|
|
|
L-glutamine + 2-deoxy-scyllo-inosose <=> 2-Oxoglutaramate + 2-deoxy-scyllo-inosamine
|
2.6.1.100
L-glutamine:2-deoxy-scyllo-inosose aminotransferase
2.6.1.50
glutamine---scyllo-inositol transaminase
|
–
–
|
| |
BRENDA:
BR50432
KEGG:
R08890
MetaCyc:
RXN-13117
|
|
|
|
UDP-glucose + 2-deoxystreptamine <=> 2''-deamino-2''-hydroxyparomamine + UDP + H+
|
2.4.1.284
2-deoxystreptamine glucosyltransferase
|
–
|
| |
BRENDA:
BR50180
KEGG:
R10096
MetaCyc:
RXN-13121
|
|
|
|
2''-N-acetylparomamine + H2O <=> paromamine + acetate
|
3.5.1.112
2'-N-acetylparomamine deacetylase
|
–
|
| |
BRENDA:
BR50322
KEGG:
R08895
MetaCyc:
RXN-13123
|
|
|
|
neamine + UDP-alpha-D-kanosamine <=> kanamycin_B + UDP + H+
|
2.4.1.301
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
|
–
|
| |
BRENDA:
BR50648
KEGG:
R10425
MetaCyc:
RXN-13147
|
|
|
|
2''-deamino-2''-hydroxyparomamine + O2 <=> 2''-deamino-2''-hydroxy-6''-dehydroparomamine + H2O2
|
1.1.3
|
–
|
| |
KEGG:
R10207
MetaCyc:
RXN-13166
|
|
|
|
2''-deamino-2''-hydroxyneamine + UDP-alpha-D-kanosamine <=> kanamycin_A + UDP + H+
|
2.4.1.301
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
|
–
|
| |
BRENDA:
BR50647
KEGG:
R10424
MetaCyc:
RXN-13125
|
|
|
|
kanamycin_B + 2-oxoglutarate + O2 <=> 2''-dehydrokanamycin_A + succinate + NH3 + CO2
|
1.14.11.37
kanamycin B dioxygenase
|
–
|
| |
BRENDA:
BR50514
KEGG:
R10312
MetaCyc:
RXN-14401
|
|
|
|
D-glucose_6-phosphate <=> 2-deoxy-scyllo-inosose + phosphate
|
4.2.3.124
2-deoxy-scyllo-inosose synthase
|
–
|
| |
BRENDA:
BR50122
KEGG:
R08617
MetaCyc:
RXN-13116
SABIO-RK:
12961
|
|
|
|
2''-deamino-2''-hydroxy-6''-dehydroparomamine + L-glutamate <=> 2''-deamino-2''-hydroxyneamine + 2-oxoglutarate
|
2.6.1.94
2'-deamino-2'-hydroxyneamine transaminase
|
–
|
| |
BRENDA:
BR50193
KEGG:
R10094
MetaCyc:
RXN-13127
|
|
|
|
kanamycin_A + NADP+ <=> 2''-dehydrokanamycin_A + NADPH + H+
|
1.1.1.355
2'-dehydrokanamycin reductase
|
–
|
| |
BRENDA:
BR50592
KEGG:
R10417
MetaCyc:
RXN-14402
|
|
|
|
neamine + 2-oxoglutarate <=> 6''-dehydroparomamine + L-glutamate
|
2.6.1.93
neamine transaminase
|
–
|
| |
BRENDA:
BR50192
KEGG:
R08897
MetaCyc:
RXN-13146
|
|
|
|
2''-deamino-2''-hydroxyparomamine + UDP-alpha-D-kanosamine <=> kanamycin_X + UDP + H+
|
2.4.1.301
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
|
–
|
| |
BRENDA:
BR50650
KEGG:
R10427
MetaCyc:
RXN-13124
|
|
|
|
UDP-glucose + neamine <=> 3''''-deamino-3''''-hydroxykanamycin_B + UDP + H+
|
2.4.1.301
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
|
–
|
| |
KEGG:
R11272
MetaCyc:
RXN-13149
|
|
|
|
paromamine + UDP-alpha-D-kanosamine <=> kanamycin_C + UDP + H+
|
2.4.1.301
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
|
–
|
| |
BRENDA:
BR50649
KEGG:
R10426
MetaCyc:
RXN-13145
|
|
|
|
UDP-N-acetyl-D-glucosamine + 2-deoxystreptamine <=> H+ + 2''-N-acetylparomamine + UDP
|
2.4.1.283
2-deoxystreptamine N-acetyl-D-glucosaminyltransferase
|
–
|
| |
BRENDA:
BR50179
KEGG:
R08894
MetaCyc:
RXN-13122
|
|
|
|
UDP-glucose + 2''-deamino-2''-hydroxyneamine <=> Kanamycin_D + UDP + H+
|
2.4.1.301
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
|
–
|
| |
KEGG:
R11271
MetaCyc:
RXN-13148
|
|
|
|
L-glutamine + 3-amino-2,3-dideoxy-scyllo-inosose <=> 2-Oxoglutaramate + 2-deoxystreptamine
|
2.6.1.101
L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase
2.6.1.50
glutamine---scyllo-inositol transaminase
|
–
–
|
| |
BRENDA:
BR50433;
BS356687
KEGG:
R08891
MetaCyc:
RXN-13119
|
|
