|
|
acyl-CoA + sphinganine <=> dihydroceramide + CoA + H+
|
2.3.1.24
sphingosine N-acyltransferase
2.3.1.291
sphingoid base N-palmitoyltransferase
2.3.1.297
very-long-chain ceramide synthase
|
–
–
–
|
| |
BRENDA:
BS320738;
BS449519
KEGG:
R06517
MetaCyc:
RXN-7792
|
|
|
|
sphinganine + NADP+ <=> 3-dehydrosphinganine + NADPH + H+
|
1.1.1.102
3-dehydrosphinganine reductase
|
–
|
| |
BRENDA:
BR29168
KEGG:
R02978
MetaCyc:
3-DEHYDROSPHINGANINE-REDUCTASE-RXN;
RXN-20505
|
|
|
|
dihydroceramide + O2 + ferricytochrome_b5 + H+ <=> ceramide + ferricytochrome_b5 + H2O
|
1.14.19.17
sphingolipid 4-desaturase
|
–
|
| |
BRENDA:
BR51368
KEGG:
R06519
MetaCyc:
RXN-16332
|
|
|
|
palmitoyl-CoA + L-serine + H+ <=> 3-dehydrosphinganine + CO2 + CoA
|
2.3.1.50
serine C-palmitoyltransferase
|
–
|
| |
BRENDA:
BR44052
KEGG:
R01281
MetaCyc:
SERINE-C-PALMITOYLTRANSFERASE-RXN
|
|
