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L-lysine fermentation to acetate and butanoate

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
L-erythro-3,5-diaminohexanoate + NAD+ + H2O <=> H+ + (S)-5-amino-3-oxohexanoate + NH3 + NADH 1.4.1.11 L-erythro-3,5-diaminohexanoate dehydrogenase

ATP + acetate <=> ADP + acetyl_phosphate 2.1.2.2 phosphoribosylglycinamide formyltransferase
2.7.2.1 acetate kinase
2.7.2.15 propionate kinase
2.7.2.2 carbamate kinase




butyryl-CoA + acetoacetate <=> Butyrate + acetoacetyl-CoA 2.8.3.9 butyrate---acetoacetate CoA-transferase

butyryl-CoA + NAD+ + reduced_ferredoxin_[iron-sulfur]_cluster <=> crotonyl-CoA + NADH + oxidized_ferredoxin 1.3.1.109 butanoyl-CoA dehydrogenase (NAD+, ferredoxin)

L-beta-Lysine <=> L-erythro-3,5-diaminohexanoate 5.4.3.3 lysine 5,6-aminomutase
5.4.3.4 D-lysine 5,6-aminomutase


L-3-aminobutanoyl-CoA <=> NH3 + crotonyl-CoA 4.3.1.14 3-aminobutyryl-CoA ammonia-lyase

(S)-5-amino-3-oxohexanoate + acetyl-CoA <=> L-3-aminobutanoyl-CoA + acetoacetate 2.3.1.247 3-keto-5-aminohexanoate cleavage enzyme

L-lysine <=> L-beta-Lysine 5.4.3.2 lysine 2,3-aminomutase

phosphate + acetyl-CoA <=> acetyl_phosphate + CoA 2.3.1.19 phosphate butyryltransferase
2.3.1.222 phosphate propanoyltransferase
2.3.1.8 phosphate acetyltransferase



acetyl-CoA <=> acetoacetyl-CoA + CoA 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
2.3.1.155 acetyl-CoA C-myristoyltransferase
2.3.1.16 acetyl-CoA C-acyltransferase
2.3.1.38 [acyl-carrier-protein] S-acetyltransferase
2.3.1.9 acetyl-CoA C-acetyltransferase





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