|
|
2-isopropylmaleate + H2O <=> (2S)-2-isopropylmalate
|
4.2.1.33
3-isopropylmalate dehydratase
|
–
|
| |
BRENDA:
BR413;
BR49521;
BS1964
KEGG:
R03968;
R04001
MetaCyc:
3-ISOPROPYLMALISOM-RXN;
RXN-8991
SABIO-RK:
3704;
3736
|
|
|
|
2-isopropylmaleate + H2O <=> (2S)-2-isopropylmalate
|
4.2.1.33
3-isopropylmalate dehydratase
|
–
|
| |
BRENDA:
BR413;
BR49521;
BS1964
KEGG:
R03968;
R04001
MetaCyc:
3-ISOPROPYLMALISOM-RXN;
RXN-8991
SABIO-RK:
3704;
3736
|
|
|
|
(2R,3S)-3-isopropylmalate + NAD+ <=> (2S)-2-isopropyl-3-oxosuccinate + NADH + H+
|
1.1.1.85
3-isopropylmalate dehydrogenase
|
–
|
| |
BRENDA:
BR47597;
BS373119
KEGG:
R04426
MetaCyc:
3-ISOPROPYLMALDEHYDROG-RXN
|
|
|
|
H+ + (2S)-2-isopropyl-3-oxosuccinate <=> 4-methyl-2-oxopentanoate + CO2
|
0.0.0.0
1.1.1.85
3-isopropylmalate dehydrogenase
|
–
–
|
| |
BRENDA:
BR52894
KEGG:
R01652
MetaCyc:
RXN-7800
|
|
|
|
L-leucine + 2-oxoglutarate <=> L-glutamate + 4-methyl-2-oxopentanoate
|
2.6.1.1
aspartate transaminase
2.6.1.2
alanine transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.6
leucine transaminase
2.6.1.67
2-aminohexanoate transaminase
2.6.1.9
histidinol-phosphate transaminase
|
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR47691
KEGG:
R01090
MetaCyc:
BRANCHED-CHAINAMINOTRANSFERLEU-RXN
SABIO-RK:
1352
|
|
|
|
2-oxoisovalerate + acetyl-CoA + H2O <=> H+ + (2S)-2-isopropylmalate + CoA
|
2.3.3.13
2-isopropylmalate synthase
2.3.3.17
methylthioalkylmalate synthase
|
–
–
|
| |
BRENDA:
BR47381;
BS353415;
BS375022;
BS438748
KEGG:
R01213
MetaCyc:
2-ISOPROPYLMALATESYN-RXN
SABIO-RK:
545
|
|
