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L-isoleucine degradation III (oxidative Stickland reaction)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
L-isoleucine + 2-oxoglutarate <=> L-glutamate + (S)-3-methyl-2-oxopentanoate 2.6.1.42 branched-chain-amino-acid transaminase
2.6.1.67 2-aminohexanoate transaminase


(S)-3-methyl-2-oxopentanoate + CoA + oxidized_ferredoxin <=> (S)-2-methylbutanoyl-CoA + CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.2.7.7 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)

(S)-2-methylbutanoyl-CoA + H2O <=> 2-methylbutanoate + CoA + H+ 3.1.2

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