|
|
H+ + pyruvate + 2-oxobutyrate <=> (S)-2-hydroxy-2-ethyl-3-oxobutanoate + CO2
|
2.2.1.6
acetolactate synthase
|
–
|
| |
BRENDA:
BS386670;
BS454179
KEGG:
R08648
MetaCyc:
ACETOOHBUTSYN-RXN
SABIO-RK:
6688
|
|
|
|
2R,3R-2,3-dihydroxy-3-methylpentanoate <=> (S)-3-methyl-2-oxopentanoate + H2O
|
4.2.1.9
dihydroxy-acid dehydratase
|
–
|
| |
BRENDA:
BS453486
KEGG:
R05070
MetaCyc:
DIHYDROXYMETVALDEHYDRAT-RXN
|
|
|
|
L-isoleucine + 2-oxoglutarate <=> L-glutamate + (S)-3-methyl-2-oxopentanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.67
2-aminohexanoate transaminase
|
–
–
|
| |
BRENDA:
BS356522;
BS452227
KEGG:
R02199
MetaCyc:
BRANCHED-CHAINAMINOTRANSFERILEU-RXN
SABIO-RK:
2171;
9086
|
|
|
|
2R,3R-2,3-dihydroxy-3-methylpentanoate + NADP+ <=> (S)-2-hydroxy-2-ethyl-3-oxobutanoate + NADPH + H+
|
1.1.1.383
ketol-acid reductoisomerase [NAD(P)+]
|
–
|
| |
MetaCyc:
RXN-16062
|
|
|
|
2-oxobutyrate + oxidized_ferredoxin + CoA <=> propionyl-CoA + reduced_ferredoxin_[iron-sulfur]_cluster + CO2 + H+
|
1.2.7.1
pyruvate synthase
1.2.7.11
2-oxoacid oxidoreductase (ferredoxin)
1.2.7.7
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
|
–
–
–
|
| |
BRENDA:
BS189350
KEGG:
R01199
MetaCyc:
2-OXOBUTYRATE-SYNTHASE-RXN
|
|
|
|
CoA + propionate + ATP <=> propionyl-CoA + diphosphate + AMP
|
6.2.1.1
acetate---CoA ligase
6.2.1.17
propionate---CoA ligase
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.30
phenylacetate---CoA ligase
6.2.1.36
3-hydroxypropionyl-CoA synthase
6.2.1.44
3-(methylthio)propionyl---CoA ligase
|
–
–
–
–
–
–
|
| |
BRENDA:
BR68
KEGG:
R00925
MetaCyc:
PROPIONATE--COA-LIGASE-RXN
SABIO-RK:
1245
|
|
