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2-heptyl-3-hydroxy-4(1H)-quinolone biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
anthranilate + CoA + ATP <=> 2-aminobenzoyl-CoA + AMP + diphosphate 6.2.1.2 medium-chain acyl-CoA ligase
6.2.1.25 benzoate---CoA ligase
6.2.1.32 anthranilate---CoA ligase



1-(2-aminophenyl)decane-1,3-dione <=> 2-heptyl-4(1H)-quinolone + H2O 2.3.1.230 2-heptyl-4(1H)-quinolone synthase

2-aminobenzoylacetate + [PqsC_protein]-S-octanoyl-L-cysteine + H+ <=> 1-(2-aminophenyl)decane-1,3-dione + [PqsC_protein]-L-cysteine + CO2 not assigned

2-aminobenzoylacetyl-CoA + H2O <=> 2-aminobenzoylacetate + CoA + H+ 3.1.2.32 2-aminobenzoylacetyl-CoA thioesterase

octanoyl-CoA + [PqsC_protein]-L-cysteine <=> [PqsC_protein]-S-octanoyl-L-cysteine + CoA not assigned

[PqsD_protein]-S-anthraniloyl-L-cysteine + malonyl-CoA + H+ <=> 2-aminobenzoylacetyl-CoA + CO2 + [PqsD_protein]-L-cysteine not assigned

2-heptyl-4(1H)-quinolone + NADH + O2 + H+ <=> 2-heptyl-3-hydroxy-4(1H)-quinolone + NAD+ + H2O 1.14.13.182 2-heptyl-3-hydroxy-4(1H)-quinolone synthase

2-aminobenzoyl-CoA + [PqsD_protein]-L-cysteine <=> [PqsD_protein]-S-anthraniloyl-L-cysteine + CoA not assigned

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