Copied!

Pathway Search



(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
(3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA <=> (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + H2O 4.2.1.134 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

malonyl-CoA + Arachidonoyl-CoA + H+ <=> (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA + CO2 2.3.1

(7Z,10Z,13Z,16Z)-Docosatetraenoyl-CoA + NADP+ <=> (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase

(3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA + NADP+ <=> (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase

(7Z,10Z,13Z,16Z)-Docosatetraenoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> (4Z,7Z,10Z,13Z,16Z)-Docosapentaenoyl-CoA + H2O + ferricytochrome_b5 1.14.19

Visualization of the pathway