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beta-Alanine metabolism

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
1,3-diaminopropane + H2O + O2 <=> 3-aminopropionaldehyde + NH3 + H2O2 1.4.3.10 putrescine oxidase
1.4.3.21 primary-amine oxidase
1.4.3.22 diamine oxidase



malonate_semialdehyde + L-alanine <=> beta-Alanine + pyruvate 2.6.1.113 putrescine---pyruvate transaminase
2.6.1.18 beta-alanine---pyruvate transaminase
2.6.1.2 alanine transaminase
2.6.1.40 (R)-3-amino-2-methylpropionate---pyruvate transaminase
2.6.1.77 taurine---pyruvate aminotransferase





beta-Ala-Lys + H2O <=> beta-Alanine + L-lysine 3.4.13.4 Xaa-Arg dipeptidase

carnosine + H2O <=> beta-Alanine + L-histidine 3.4.11.25 beta-peptidyl aminopeptidase
3.4.13.18 cytosol nonspecific dipeptidase
3.4.13.20 beta-Ala-His dipeptidase
3.4.13.5 Xaa-methyl-His dipeptidase




beta-Alanine + L-histidine + ATP <=> H+ + carnosine + ADP + phosphate 6.3.2.11 carnosine synthase

ATP + L-arginine + beta-Alanine <=> ADP + phosphate + beta-Ala-Arg 6.3.2.11 carnosine synthase
6.3.2.49 L-alanine---L-anticapsin ligase


spermidine + O2 + H2O <=> putrescine + 3-aminopropionaldehyde + H2O2 1.5.3.16 spermine oxidase
1.5.3.17 non-specific polyamine oxidase


malonate_semialdehyde + CoA + NAD+ <=> acetyl-CoA + CO2 + NADH 1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)


NAD+ + H2O + malonate_semialdehyde <=> malonate + NADH + H+ 1.2.1.15 malonate-semialdehyde dehydrogenase
1.2.1.21 glycolaldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase




beta-Alanine + (R)-pantoate + ATP <=> H+ + pantothenate + diphosphate + AMP 6.3.2.1 pantoate---beta-alanine ligase (AMP-forming)

4-Aminobutyraldehyde + NAD+ + H2O <=> 4-aminobutanoate + NADH + H+ 1.2.1
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.47 4-trimethylammoniobutyraldehyde dehydrogenase
1.2.1.54 gamma-guanidinobutyraldehyde dehydrogenase
1.2.1.8 betaine-aldehyde dehydrogenase







5,6-dihydrouracil + NAD+ <=> Uracil + NADH + H+ 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+)
1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)


bithionol <=> acryloyl-CoA + H2O 4.2.1
4.2.1.116 3-hydroxypropionyl-CoA dehydratase
4.2.1.17 enoyl-CoA hydratase



beta-Alanine + 2-oxoglutarate <=> malonate_semialdehyde + L-glutamate 2.6.1.19 4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2 alanine transaminase
2.6.1.22 (S)-3-amino-2-methylpropionate transaminase
2.6.1.55 taurine---2-oxoglutarate transaminase




ATP + L-lysine + beta-Alanine <=> ADP + phosphate + beta-Ala-Lys 6.3.2.11 carnosine synthase

H2O + anserine <=> 1-methylhistidine + beta-Alanine 3.4.13.20 beta-Ala-His dipeptidase
3.4.13.5 Xaa-methyl-His dipeptidase


bithionol + H2O <=> H+ + 3-hydroxypropionate + CoA 3.1.2.4 3-hydroxyisobutyryl-CoA hydrolase

H+ + L-aspartate <=> beta-Alanine + CO2 4.1.1.11 aspartate 1-decarboxylase
4.1.1.15 glutamate decarboxylase
4.1.1.25 tyrosine decarboxylase
4.1.1.29 sulfinoalanine decarboxylase




5,6-dihydrouracil + NADP+ <=> Uracil + NADPH + H+ 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+)
1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)


H2O + 5,6-dihydrouracil <=> H+ + N-Carbamoyl-beta-alanine 3.5.2.16 maleimide hydrolase
3.5.2.2 dihydropyrimidinase


malonate_semialdehyde <=> propynoate + H2O 4.2.1.27 acetylenecarboxylate hydratase

acetyl-CoA + malonate <=> acetate + malonyl-CoA 2.8.3.3 malonate CoA-transferase

spermidine + O2 + H2O <=> 1,3-diaminopropane + 4-Aminobutyraldehyde + H2O2 1.4.3.10 putrescine oxidase
1.5.3.14 polyamine oxidase (propane-1,3-diamine-forming)
1.5.99.6 spermidine dehydrogenase



3-aminopropionaldehyde + NAD+ + H2O <=> H+ + beta-Alanine + NADH 1.2.1
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase






flavin + propionyl-CoA <=> reduced_flavodoxin + acryloyl-CoA 1.3.8.1 short-chain acyl-CoA dehydrogenase

propionyl-CoA + O2 <=> acryloyl-CoA + H2O2 1.3.3.6 acyl-CoA oxidase

H+ + malonyl-CoA <=> CO2 + acetyl-CoA 2.3.1.226 carboxymethylproline synthase
2.3.1.74 chalcone synthase
4.1.1.87 malonyl-S-ACP decarboxylase
4.1.1.9 malonyl-CoA decarboxylase




3-hydroxypropionate + NAD+ <=> malonate_semialdehyde + NADH + H+ 1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+)
1.1.1.31 3-hydroxyisobutyrate dehydrogenase
1.1.1.59 3-hydroxypropionate dehydrogenase
1.1.1.60 2-hydroxy-3-oxopropionate reductase




beta-Ala-Arg + H2O <=> beta-Alanine + 2-amino-5-guanidinovalerate 3.4.13.18 cytosol nonspecific dipeptidase
3.4.13.4 Xaa-Arg dipeptidase


NADP+ + H2O + malonate_semialdehyde <=> malonate + NADPH + H+ 1.2.1.15 malonate-semialdehyde dehydrogenase
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)



ATP + 1-methylhistidine + beta-Alanine <=> ADP + phosphate + anserine 6.3.2.11 carnosine synthase

spermine + O2 + H2O <=> spermidine + 3-aminopropionaldehyde + H2O2 1.5.3.16 spermine oxidase
1.5.3.17 non-specific polyamine oxidase


N-Carbamoyl-beta-alanine + H2O + H+ <=> beta-Alanine + NH3 + CO2 3.5.1.6 beta-ureidopropionase

malonate_semialdehyde + CoA + NADP+ <=> acetyl-CoA + CO2 + NADPH 1.2.1
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)


(R)-4-phosphopantoate + beta-Alanine + ATP <=> (R)-4''-phosphopantothenate + AMP + diphosphate + H+ 6.3.2.36 4-phosphopantoate---beta-alanine ligase

beta-alanyl-CoA <=> NH3 + acryloyl-CoA 4.3.1.6 beta-alanyl-CoA ammonia-lyase

N-Acetyl-beta-alanine + H2O <=> beta-Alanine + acetate 3.5.1.21 N-acetyl-beta-alanine deacetylase

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