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CO2 fixation in Crenarchaeota

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
acetyl-CoA + 4-hydroxybutyrate <=> acetate + 4-hydroxybutanoyl-CoA 2.8.3
2.8.3.1 propionate CoA-transferase


(S)-3-hydroxybutyryl-CoA + NAD+ <=> acetoacetyl-CoA + NADH + H+ 1.1.1.178 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
1.1.1.36 acetoacetyl-CoA reductase



ATP + acetyl-CoA + HCO3- <=> ADP + phosphate + malonyl-CoA + H+ 6.4.1.2 acetyl-CoA carboxylase
6.4.1.3 propionyl-CoA carboxylase
6.4.1.4 methylcrotonoyl-CoA carboxylase



(S)-3-hydroxybutyryl-CoA <=> H2O + crotonyl-CoA 1.3.8.7 medium-chain acyl-CoA dehydrogenase
4.2.1.116 3-hydroxypropionyl-CoA dehydratase
4.2.1.150 short-chain-enoyl-CoA hydratase
4.2.1.17 enoyl-CoA hydratase




4-hydroxybutanoyl-CoA <=> crotonyl-CoA + H2O 4.2.1.120 4-hydroxybutanoyl-CoA dehydratase

propionyl-CoA + NADP+ <=> acryloyl-CoA + NADPH + H+ 1.3.1
1.3.1.84 acrylyl-CoA reductase (NADPH)
1.3.1.95 acrylyl-CoA reductase (NADH)



malonate_semialdehyde + CoA + NADP+ <=> malonyl-CoA + NADPH + H+ 1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
1.2.1.75 malonyl-CoA reductase (malonate semialdehyde-forming)


3-hydroxypropionate + NADP+ <=> malonate_semialdehyde + NADPH + H+ 1.1.1
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.276 serine 3-dehydrogenase (NADP+)
1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+)




ATP + propionyl-CoA + HCO3- <=> H+ + (S)-methylmalonyl-CoA + phosphate + ADP 6.4.1.2 acetyl-CoA carboxylase
6.4.1.3 propionyl-CoA carboxylase


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