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2-methylcitrate cycle II

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate <=> (Z)-2-methylaconitate + H2O 4.2.1.3 aconitate hydratase
4.2.1.99 2-methylisocitrate dehydratase


propionyl-CoA + H2O + oxaloacetate <=> (2S,3S)-methylcitrate + CoA + H+ 2.3.3.16 citrate synthase (unknown stereospecificity)
2.3.3.5 2-methylcitrate synthase


(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate <=> succinate + pyruvate 4.1.3.1 isocitrate lyase
4.1.3.30 methylisocitrate lyase


CoA + propionate + ATP <=> propionyl-CoA + diphosphate + AMP 6.2.1.1 acetate---CoA ligase
6.2.1.17 propionate---CoA ligase
6.2.1.2 medium-chain acyl-CoA ligase
6.2.1.30 phenylacetate---CoA ligase
6.2.1.36 3-hydroxypropionyl-CoA synthase
6.2.1.44 3-(methylthio)propionyl---CoA ligase






(2S,3S)-methylcitrate <=> H2O + 2-methyl-trans-aconitate 4.2.1.117 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
4.2.1.79 2-methylcitrate dehydratase


2-methyl-trans-aconitate <=> (Z)-2-methylaconitate 5.3.3

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