Pathway Search

2-methylcitrate cycle I

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
(2S,3S)-methylcitrate <=> (Z)-2-methylaconitate + H2O 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) 2-methylcitrate dehydratase

propionyl-CoA + H2O + oxaloacetate <=> (2S,3S)-methylcitrate + CoA + H+ citrate synthase (unknown stereospecificity) 2-methylcitrate synthase

(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate <=> succinate + pyruvate isocitrate lyase methylisocitrate lyase

(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate <=> (Z)-2-methylaconitate + H2O aconitate hydratase 2-methylisocitrate dehydratase

CoA + propionate + ATP <=> propionyl-CoA + diphosphate + AMP acetate---CoA ligase propionate---CoA ligase medium-chain acyl-CoA ligase phenylacetate---CoA ligase 3-hydroxypropionyl-CoA synthase 3-(methylthio)propionyl---CoA ligase

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